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There is a direct correlation between patients with periodontal disease and negative cognitive decline or Alzheimer’s disease. Research has proven that those who suffer from Alzheimer’s/dementia have a reduced dentition which negatively impacts masticatory function. With impaired masticatory function, it leads to poor nutrition which has a direct effect on cerebral stimulation and blood flow which worsens the effects of Alzheimer’s. The bacteria that is present during periodontitis, causes a spike in inflammatory cytokines. These cytokines invade the brain and trigger CNS inflammation which leads to cognitive decline.
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Labonte, Lexis and Cole, Jaycee, "Periodontal Disease And Alzheimer’s Disease" (2023). Dental Hygiene Student Research Posters. 21.