Faculty Advisor(s)

Nan Solomons

Associated Course

HIN 785

Publication Date




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Differences and similarities are examined among SARS-CoV-2, SARS-CoV-1, MERS and influenza A, in the context of transmissibility. Characteristics specific to the respective pathogens prove invaluable as they set the stage for intervention and management. SARS-CoV-2 bears similarities to other recently emerged infectious diseases in basic virologic ways, yet is distinctly different in terms of viral transmission dynamics. These differences arise from genomic qualities and properties specific to the virus. As ACE2 receptors are determinants for attachment and spread of the virus, and their role throughout tissues in the body is vast, an understanding of organ-level pathogenesis of SARS-CoV-2 is crucial to effectively treat and (hopefully) neutralize SARS-CoV-2. Certain populations are identified as higher risk populations for severity of illness due to factors including age, gender and obesity. Therapies and treatments (including social responsibility behaviors) are described in current practice.


© 2020 Debbie Calabrese


Health Information Technology | Medicine and Health Sciences

Material Type

Literature Review

Comparison Of SARS-CoV-2 To SARS-CoV, MERS, And Influenza A: A Systematic Review



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