Faculty Advisor(s)

Elisha Coppens

Document Type


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© 2022 Novisi Abba


Pain is undoubtedly one of the most undesirable outcomes associated with cesarean section in parturients. The most effective post-cesarean section pain relief option should prioritize maternal, fetal, and neonatal safety, with minimal to no medication transfer to the fetus and neonate. In obstetric anesthesia, neuraxial approaches, with the inclusion of adjuncts like clonidine for pain management may provide some additional benefits. Consequently, obstetric anesthesia practitioners have increasingly used intrathecal clonidine to alleviate post-cesarean section pain. This manuscript examines whether intrathecal clonidine, when combined with hyperbaric bupivacaine and/or opioids (fentanyl and/or preservative-free morphine), has a sustained analgesic effect in parturients following cesarean delivery under spinal anesthesia. A literature review of relevant articles was conducted. Results of the literature review suggested that the addition of intrathecal clonidine to bupivacaine reduced the 24-hour morphine consumption and prolonged the subarachnoid block duration in cesarean section patients.


MSNA Capstone



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