Faculty Advisor(s)

Michael Conti

Document Type


Publication Date

Spring 2023


© 2023 the Author


Patients undergoing elective spinal fusion surgeries often experience moderate to severe postoperative pain (Murphy et al., 2017). The use of perioperative methadone has been suggested as an effective adjunct for patients to reduce postoperative pain, decrease opioid use, and improve patient satisfaction (Murphy et al., 2017). Traditional opioid management of orthopedic spine surgeries include intermittent injections or patient-controlled analgesia devices. These approaches may cause fluctuating levels of opioids or require patient education and cooperation to be effective (Murphy & Szokol, 2019). Methadone has a much longer elimination half-life when compared to other opioids, and therefore may provide patients with a stable blood concentration of opioid to improve postoperative pain control (Murphy & Szokol, 2019). In adult patients undergoing elective spine surgery, how effective is perioperative methadone use compared to traditional opioid management in controlling postoperative pain in the first 24 hours?


MSNA Capstone



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