Amy J. Litterini
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The purpose of this case report is to describe PT interventions for an individual with a cancer diagnosis who received an allo-SCT and subsequently had long-term complications associated with cGVHD, long-term corticosteroid use, and cancer survivorship. Myelodysplastic Syndrome (MDS) is often called pre-leukemia as 1 in 3 individuals will develop Acute Myeloid Leukemia. It is a type of cancer that causes blood producing cells in bone marrow to function abnormally and causes normal blood cells to die earlier. Graft-Versus-Host-Disease (GVHD) develops in approximately 70% of patients following an allogenic stem cell transplant. Donor’s cells attack both the malignancy and the patient’s healthy cells. Treatment for acute and chronic GVHD (cGVHD) is often corticosteroids, which can have detrimental effect on muscle strength, immune function, weight, and mood.
The case report paper for this poster can be found here:
Deardorff, Alyssa and Litterini, Amy J., "Functional Mobility For A Patient With Myelodysplastic Syndrome, Chronic GVHD, And Corticosteroid Use: A Case Report" (2018). Case Report Posters. Poster 151.