Faculty Advisor(s)

Kirsten Buchanan



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Charcot-Marie-Tooth disease (CMT) is an inherited neuromuscular disease caused by mutations in genes that produce proteins involved in the structure and function of either the myelin sheath or the peripheral nerve axon. The slow degeneration of the nerves results in a decreased ability to communicate with their distant targets leading to symmetric distal muscle atrophy and weakness, hand and foot deformities, and sensory loss. There is currently no treatment that reverses or stops the progression of the disease; however, there are physical therapy (PT) interventions that reduce the level of disability in individuals with CMT. Research has shown that interval and resistance exercise can improve functional capacity, strength and activities of daily living (ADLs) in people with CMT. Myocardial infarction (MI) is often a result of coronary artery disease (CAD), which has an incidence rate of 34.6% in men over 80.10 Immediate exercise interventions in the acute care setting following an MI have shown to positively impact a patient’s functional capacity and quality of life. While rehabilitation practices for CMT and MI have been described separately, there is a paucity of research investigating the optimal physical therapy (PT) interventions for patients who have both health conditions concurrently. The purpose of this case report was to describe a progressive PT plan of care for a patient with CMT following an acute myocardial infarction (MI) in the acute and sub-acute care settings.

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Physical Therapy

Related Materials

The case report paper for this poster can be found here:


A Progressive Physical Therapy Plan Of Care For A Patient With Charcot-Marie-Tooth Disease Following Myocardial Infarction: A Case Report



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