Perspective Chapter: Multi-Omic Approaches To Vaccine Development Against Helminth Diseases
Document Type
Article
Publication Date
4-2022
Abstract
Though the past three decades have led to a renaissance in vaccine design, the development of vaccines that protect against helminth diseases remains elusive. The need for protective vaccines for humans and livestock remains urgent because of the side-effect profiles of anti-helminthic drugs and the growing incidence of antimicrobial resistance and declining efficacy. The “-omics” era has led to renewed interest in vaccine development against helminth diseases, as candidate vaccines can now be designed, evaluated, and refined in a fraction of the time previously required. In this chapter, we describe and review genomic, transcriptomic, and proteomic approaches to the design of vaccines against helminth diseases.
Recommended Citation
Daga, Vrushabh; Green, Evangeline; Ravichandran, Priyanka; Short, Meagan; and May, Meghan, "Perspective Chapter: Multi-Omic Approaches To Vaccine Development Against Helminth Diseases" (2022). Osteopathic Medicine Student Publications. 4.
https://dune.une.edu/com_studpubs/4
Comments
Chapter from open access book Parasitic Helminths and Zoonoses - From Basic to Applied Research:
Daga, V., Green, E., Ravichandran, P., Short, M., & May, M. (2022). Perspective Chapter: Multi-Omic Approaches to Vaccine Development against Helminth Diseases. IntechOpen. doi: 10.5772/intechopen.102621
Authors Daga, Green, Ravichandran, and Short were University of New England College of Osteopathic Medicine students at time of publication; author May is a member of the University of New England faculty.