Title

Efficacy Of Statin Therapy In The Elderly

Creator

Alyssa M. B. White, University of New EnglandFollow
Hillary R. Mishcon, University of New EnglandFollow
John Redwanski, University of New EnglandFollow
Ronald D. Hills Jr, University of New EnglandFollow

Files

Description

Statins are one of the most heavily prescribed medications. The 2018 ACC/AHA guidelines support statin therapy for most older adults, but recommendations are less clear for those over 75. The literature was systematically reviewed for evidence of the efficacy of statin treatment in different patient populations. Significant evidence was found supporting a decreasing association between low-density lipoprotein cholesterol (LDL-C) and mortality as well as decreasing statin efficacy with increasing age. The consequences of unnecessary statin therapy can be severe for older adults. Improved methods for evaluating atherosclerotic cardiovascular disease (ASCVD) risk, such as using negative markers to help identify those who may not benefit from statin therapy, should be more widely employed.

Publication Date

2019

Disciplines

Pharmacy and Pharmaceutical Sciences

Access/Rights

© 2019 The Authors

Notes

Authors White and Mishcon were University of New England Pharmacy students when this study was conducted.

Preferred Citation

White, Alyssa M. B.; Mishcon, Hillary R.; Redwanski, John; and Hills, Ronald D. Jr, "Efficacy Of Statin Therapy In The Elderly" (2019). Pharmacy Student Posters. 2.
https://dune.une.edu/pharm_studpost/2